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Chromosome bands patterns in the genome by Wendy Bickmore

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Published by Chapman & Hall, Landes Bioscience in New York, Austin, Tex .
Written in English


  • Chromosome banding.

Book details:

Edition Notes

Includes bibliographical references and index.

StatementWendy Bickmore, Jeffrey Craig.
SeriesMolecular biology intelligence unit, Molecular biology intelligence unit (Unnumbered)
ContributionsCraig, Jeffrey.
LC ClassificationsQH600 .B535 1997
The Physical Object
Pagination185 p. :
Number of Pages185
ID Numbers
Open LibraryOL995740M
ISBN 101570593930, 041211741X
LC Control Number96034369

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  Chromosome 6 book. Read reviews from the world's largest community for readers. Behind the headlines on cloning--Dr. Robin Cook blends fact with fict /5. Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. People normally have two copies of this chromosome. Chromosome 13 spans about million base pairs (the building material of DNA) and represents between and 4% of the total DNA in mere position: Acrocentric, ( Mbp). Unambiguous chromosome identification depends on the use of various staining techniques. Staining is responsible for the alternating dark and light bands on the chromosomes noted in Figure B. The most routinely used technique stains the metaphase chromosomes with Giemsa (after using the enzyme trypsin to digest proteins). Each chromosome pair stains with . Our genetic information is stored in 23 pairs of chromosomes that vary widely in size and shape. Chromosome 1 is the largest and is over three times bigger than chromosome The 23rd pair of chromosomes are two special chromosomes, X and Y, that determine our sex. Females have a pair of X chromosomes (46, XX), whereas males have one X and one Y chromosomes (46, XY).

Chromosome banding refers to alternating light and dark regions along the length of a chromosome, produced after staining with a dye. A band is defined as the part of a chromosome that is clearly distinguishable from its adjacent segments by appearing darker or lighter with the use of one or more banding techniques. Thus, the bright Q-bands correspond to the dark G-bands, which in turn appear to be identical with the R-light bands. This does not exclude the possibility that some similar-appearing bands have different properties. Thus, the chromosome ends apparently differ from other Q-dark bands (Ambros and Sumner, ; Korenberg and Rykowski, ).Author: Eeva Therman, Millard Susman. The mammalian chromosome is longitudinally heterogeneous in structure and function and this is the basis for the specific banding patterns produced by various chromosome staining techniques.   Chromosome banding is the transverse bands that appear on chromosomes as a result of various differential staining techniques. Differential stains impart colors to tissues, so that they may be studied under a microscope. Chromosomes are thread-like structures of long deoxyribonucleic acid (DNA.

1. The Metaphase Chromosome Chromosome Banding Techniques DNA Sequence and Chromosome Bands The Chromatin Structure of Chromosome Bands The Activity of Chromosome Bands at Interphase Heterochromatin and Other Extremes of Chromatin Flavor The Chromosome Band: Origins, Perspectives and Future Prospects. Series Title. G-banding method stains positively % of the chromosome surface, and a total of G-bands (77 positive, 65 negative and 7 variable) has been recorded in . Various chemical and physical treatments, followed by incorporation of dye, may be used to produce a pattern of specific transverse light and dark bands on condensed metaphase chromosomes. These bands correspond to clusters of GC- and AT‐rich, and early- and late‐replicating DNA, respectively, and thus reflect the underlying longitudinal. Chromosome, the microscopic threadlike part of the cell that carries hereditary information in the form of genes.A defining feature of any chromosome is its compactness. For instance, the 46 chromosomes found in human cells have a combined length of nm (1 nm = 10 − 9 metre); if the chromosomes were to be unraveled, the genetic material they contain would measure .